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Article

Impact of JAK2V617F Mutation Burden on Disease Phenotype in Chinese Patients with JAK2V617F-positive Polycythemia Vera (PV) and Essential thrombocythemia (ET).

International journal of medical sciences - 1 Jan 2016

Zhao Shixiang, Zhang Xiang, Xu Yang, Feng Yufeng, Sheng Wenhong, Cen Jiannong, Wu Depei, Han Yue

Abstract excerpt

Most patients with polycythemia vera (PV) and half of essential thrombocythemia (ET) possess an activating JAK2V617F mutation. The objective of this study was to better define the effect of JAK2V617F mutant allele burden on clinical phenotypes in Chinese patients, especially thrombosis. By real-time polymerase chain reaction (RT-PCR), the JAK2V617F mutation burden was detected in 170 JAK2V617F-positive patients,...

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Identifiers

PMID: 26917989
DOI: 10.7150/ijms.10539
PMCID: PMC4747874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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