Article
JAK2V617F allele burden and thrombosis: a direct comparison in essential thrombocythemia and polycythemia vera.
Experimental hematology - 1 Sept 2009
Carobbio Alessandra, Finazzi Guido, Antonioli Elisabetta, Guglielmelli Paola, Vannucchi Alessandro M, Dellacasa Chiara M, Salmoiraghi Silvia, Delaini Federica, Rambaldi Alessandro, Barbui Tiziano
Abstract excerpt
OBJECTIVE: A direct comparison of the incidence and risk factors of major thrombosis in essential thrombocythemia (ET) and polycythemia vera (PV) according to their respective JAK2V617F allele burden is the object of this study. MATERIALS AND METHODS: We compared the rate (%/patients/year) of major thrombosis in 867 ET patients (57% JAK2V617F) with that of 415 PV patients (all JAK2V617F) and examined risk...
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