Chemically unambiguous peptide immunogen: preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system.

doi:10.1016/0161-5890(91)90131-3

Article

Chemically unambiguous peptide immunogen: preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system.

Molecular immunology - 1 Jun 1991

Lu Y A, Clavijo P, Galantino M, Shen Z Y, Liu W, Tam J P

Abstract excerpt

We described a novel and simple approach to prepare chemically unambiguous peptide immunogen using the multiple antigen peptide (MAP) approach. This approach requires the conjugation of two purified components: a chloroacetylated oligomeric lysine core matrix and a synthetic peptide containing cy...

Topics

Amino Acid Sequence
Animals
Antibody Specificity
Enzyme-Linked Immunosorbent Assay
Molecular Sequence Data
Mutation
Peptides
Rabbits
Transforming Growth Factor alpha
Vaccines, Synthetic

Chemically unambiguous peptide immunogen: preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system.

Abstract excerpt

Topics

Discuss the evidence