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Article

Folate and clefts of the lip and palate--a U.K.-based case-control study: Part II: Biochemical and genetic analysis.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 2008

Little J, Gilmour M, Mossey P A, Fitzpatrick D, Cardy A, Clayton-Smith J, Hill A, Duthie S J, Fryer A E, Molloy A M, Scott J M

Abstract excerpt

OBJECTIVE: To investigate associations between nonsyndromic oral clefts and biochemical measures of folate status and the MTHFR C677T variant in the United Kingdom, where there has been no folic acid fortification program. METHOD: Dietary details were obtained from the mothers of 112 cases of cleft lip with or without cleft palate (CL+/-P), 78 cleft palate only (CP) cases, and 248 unaffected infants. Infant and...

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PMID: 18616362
DOI: 10.1597/06-151.1

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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