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Article

EphB receptors couple dendritic filopodia motility to synapse formation.

Neuron - 10 Jul 2008

Kayser Matthew S, Nolt Mark J, Dalva Matthew B

Abstract excerpt

Motile dendritic filopodial processes are thought to be precursors of spine synapses, but how motility relates to cell-surface cues required for axon-dendrite recognition and synaptogenesis remains unclear. We demonstrate with dynamic imaging that loss of EphBs results in reduced motility of filopodia in cultured cortical neurons and brain slice. EphB knockdown and rescue experiments during different...

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Identifiers

PMID: 18614029
DOI: 10.1016/j.neuron.2008.05.007
PMCID: PMC2617787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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