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Article

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus.

The Journal of cell biology - 22 Dec 2003

Henkemeyer Mark, Itkis Olga S, Ngo Michelle, Hickmott Peter W, Ethell Iryna M

Abstract excerpt

Here, using a genetic approach, we dissect the roles of EphB receptor tyrosine kinases in dendritic spine development. Analysis of EphB1, EphB2, and EphB3 double and triple mutant mice lacking these receptors in different combinations indicates that all three, although to varying degrees, are involved in dendritic spine morphogenesis and synapse formation in the hippocampus. Hippocampal neurons lacking EphB...

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Identifiers

PMID: 14691139
DOI: 10.1083/jcb.200306033
PMCID: PMC1435730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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