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Article

LPA and PLG sequence variation and kringle IV-2 copy number in two populations.

Human heredity - 1 Jan 2008

Crawford Dana C, Peng Ze, Cheng Jan-Fang, Boffelli Dario, Ahearn Magdalena, Nguyen Dan, Shaffer Tristan, Yi Qian, Livingston Robert J, Rieder Mark J, Nickerson Deborah A

Abstract excerpt

BACKGROUND/AIMS: Lp(a) levels have long been recognized as a potential risk factor for coronary heart disease that is almost completely under genetic control. Much of the genetics impacting Lp(a) levels has been attributed to the highly polymorphic LPA kringle IV-2 copy number variant, and most of the variance in Lp(a) levels in populations of European-descent is inversely correlated with kringle IV copy number....

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Source

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Identifiers

PMID: 18612205
DOI: 10.1159/000143403
PMCID: PMC2861532

Genes

LPA
PLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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