Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells.

Journal of atherosclerosis and thrombosis - 1 Jun 2008

Saito Eiji, Wachi Hiroshi, Sato Fumiaki, Seyama Yoshiyuki

Abstract excerpt

AIM: Oxysterols are found in high concentrations in advanced atherosclerotic plaques and are considered as an important factor in the development of vascular calcification. The purpose of this study was to investigate the effect of 7-ketocholesterol (7kc), a major oxysterol in plaques, on in vitro arterial calcification. METHODS: Bovine vascular smooth muscle cells (VSMCs) were cultured with inorganic phosphate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Calcium
Share to DNA Fragmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypercholesterolemia

Share to Mevalonic Acid

Share to Myocytes, Smooth Muscle

Share to Phosphates

Share to rho-Associated Kinases

Source

Identifiers

PMID: 18603819
DOI: 10.5551/jat.e556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells.PMID 18603819Read ↗

Vascular smooth muscle cell differentiation to an osteogenic phenotype involves matrix metalloproteinase-2 modulation by homocysteine.Semantic proximity Read ↗

Biology of calcification in vascular cells: intima versus media.Semantic proximity Read ↗

Plaque Calcification During Atherosclerosis Progression and Regression.Semantic proximity Read ↗

Selective Removal of 7KC by a Novel Atherosclerosis Therapeutic Candidate Reverts Foam Cells to a Macrophage-like PhenotypeSemantic proximity Read ↗

Attenuating Effects of Pyrogallol-Phloroglucinol-6,6-Bieckol on Vascular Smooth Muscle Cell Phenotype Changes to Osteoblastic Cells and Vascular Calcification Induced by High Fat Diet.Semantic proximity Read ↗

A new in vitro model to delay high phosphate-induced vascular calcification progression.Semantic proximity Read ↗

Lyso-phosphatidylcholine induces osteogenic gene expression and phenotype in vascular smooth muscle cells.Semantic proximity Read ↗

Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor γ ligands retard cultured vascular smooth muscle cells calcification induced by high glucose.Semantic proximity Read ↗

Skeletonized coronary arteries: pathophysiological and clinical aspects of vascular calcification.Semantic proximity Read ↗

Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice.Semantic proximity Read ↗

Serum IP-10 and IL-17 from Kawasaki disease patients induce calcification-related genes and proteins in human coronary artery smooth muscle cells in vitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.