Article
Murine pulmonary response to chronic hypoxia is strain specific.
Experimental lung research - 1 Aug 2008
Tada Yuji, Laudi Sven, Harral Julie, Carr Michelle, Ivester Charles, Tanabe Nobuhiro, Takiguchi Yuichi, Tatsumi Koichiro, Kuriyama Takayuki, Nichols William C, West James
Abstract excerpt
Information concerning the effects of genetic variation between different background strains on hemodynamic, morphometric, and gene expression response to hypoxia would be useful. Three strains of mice were kept in hypoxia and phenotyped followed by gene profiling analysis. Among the variables examined, hematocrit, right heart muscularization, and right ventricular systolic pressure showed a strain-specific...
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