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Article

The role of different strain backgrounds in bacterial endotoxin-mediated sensitization to neonatal hypoxic-ischemic brain damage.

Neuroscience - 17 Dec 2015

Rocha-Ferreira E, Phillips E, Francesch-Domenech E, Thei L, Peebles D M, Raivich G, Hristova M

Abstract excerpt

Genetic background is known to influence the outcome in mouse models of human disease, and previous experimental studies have shown strain variability in the neonatal mouse model of hypoxia-ischemia. To further map out this variability, we compared five commonly used mouse strains: C57BL/6, 129SVJ, BALB/c, CD1 and FVB in a pure hypoxic-ischemic setup and following pre-sensitization with lipopolysaccharide (LPS)....

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Source

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Identifiers

PMID: 26515746
DOI: 10.1016/j.neuroscience.2015.10.035
PMCID: PMC4675086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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