Article
Susceptibility to pulmonary hypertension in inbred strains of mice exposed to cigarette smoke.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2007
Nadziejko Christine, Fang Kaije, Bravo Antonio, Gordon Terry
Abstract excerpt
Cor pulmonale is a significant cause of morbidity and mortality in patients with emphysema, but it is not known whether alveolar destruction is directly involved in the disease pathogenesis. The purpose of this study was to examine the relationship between susceptibility to smoking-induced cor pulmonale and alveolar destruction in eight inbred strains of mice: 129XI/SvJ, A/J, A/HeJ, BALB/cJ, C3H/HeJ, C57BL/6J,...
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