Article
Roles of the tau gene short tandem repeats in late-onset Alzheimer's disease.
The International journal of neuroscience - 1 May 2012
Dong Shuai, Chu Lan, Liu Fang, Xu Zhu, Li Shirong, Zhang Yifan, Wang Hao, Cai Lijun, Dai Mingming
Abstract excerpt
This study assessed the roles of Tau gene short tandem repeats (STRs) nested within intron 1 (rs5820604 and rs10675722) and Apolipoprotein E (ApoE) gene polymorphisms in 70 late-onset Alzheimer's disease (AD) subjects, 70 vascular dementia (VD) subjects, and 70 normal controls (NCs) in Guizhou Han population. Our data suggest that the Tau gene STR loci rs5820604 (CA)(19) allele may increase the risk of AD,...
Read the complete abstract on PubMed