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Article

A review of the multifunctionality of angiopoietin-like 4 in eye disease

26 Jul 2018

Abstract excerpt

Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine regulating vascular permeability, angiogenesis, and inflammation. Dysregulations in these responses contribute to the pathogenesis of ischemic retinopathies such as diabetic retinopathy (DR), age-related macular degeneration (AMD), retinal vein occlusion, and sickle cell retinopathy (SCR). However, the role of ANGPTL4 in these diseases remains...

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PMID: 30049845
DOI: 10.1042/bsr20180557

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