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Liver cell lines for the study of hepatocyte functions and immunological response

17 Mar 2005

Abstract excerpt

BACKGROUND: Liver cell lines closely resembling primary hepatocyte are essential for research on hepatitis viruses and hepatocyte function. Currently used cell lines are derived from hepatic tumours and have altered gene expression. AIMS: The generation and characterisation of novel human hepatocyte lines (HHLs) derived from healthy human liver, retaining the primary hepatocyte phenotype. RESULTS: Primary...

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PMID: 15780065
DOI: 10.1111/j.1478-3231.2005.01017.x

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