Article
A1166C polymorphism of the angiotensin AT1 receptor (AT1R) gene alters endothelial response to statin treatment.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Kiliszek Marek, Burzyńska Beata, Styczyński Grzegorz, Maciag Monika, Rabczenko Daniel, Opolski Grzegorz
Abstract excerpt
BACKGROUND: The function of vascular endothelium is influenced by several factors: low-density lipoprotein (LDL) cholesterol, oxidative stress and the reninangiotensin system. METHODS: We tested the hypothesis that polymorphisms A1166C of the angiotensin AT1 receptor (AT1R) gene, C242T and A640G of the pphox22 gene (p22 phox is an essential component of NADH/NADPH oxidases) and G894T of the endothelial nitric...
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