Article
Angiotensin II type 1 receptor gene polymorphisms in humans: physiology and pathophysiology of the genotypes.
Current opinion in nephrology and hypertension - 1 Jan 2001
Duncan J A, Scholey J W, Miller J A
Abstract excerpt
Many studies have attempted to relate genetic variants of components of the renin-angiotensin system to complex diseases such as essential hypertension, cardiovascular disease and progressive renal failure. The angiotensin II type 1 receptor (AT1R) gene is an important example of this approach. Many polymorphisms of the AT1R gene have been identified, but the A1166-->C polymorphism has been the most extensively...
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