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Article

Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.

Human molecular genetics - 15 Sept 2008

Conti David V, Lee Won, Li Dalin, Liu Jinghua, Van Den Berg David, Thomas Paul D, Bergen Andrew W, Swan Gary E, Tyndale Rachel F, Benowitz Neal L, Lerman Caryn

Abstract excerpt

Although the efficacy of pharmacotherapy for tobacco dependence has been previously demonstrated, there is substantial variability among individuals in treatment response. We performed a systems-based candidate gene study of 1295 single nucleotide polymorphisms (SNPs) in 58 genes within the neuronal nicotinic receptor and dopamine systems to investigate their role in smoking cessation in a bupropion...

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Source

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Identifiers

PMID: 18593715
DOI: 10.1093/hmg/ddn181
PMCID: PMC2525499

Genes

CHRNB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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