Article
Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Aug 2012
Spruell Timothy, Colavita Guillaume, Donegan Tomas, Egawhary Marco, Hurley Michael, Aveyard Paul, Johnstone Elaine C, Murphy Michael F G, Munafò Marcus R
Abstract excerpt
INTRODUCTION: The α4β2 nicotinic receptor is of central importance in tobacco dependence, while the homomeric α7 receptor may also play a role. In this candidate gene study, we examine the association between 8 single nucleotide polymorphisms (SNPs) in genes coding for nicotinic acetylcholine receptor subunits α4 (rs1044396, rs2273504, rs2236196, and rs2273502), α7 (rs2133965 and ), and β2 ( and...
