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Article

Genomic Pattern of GSTM1 and T1 Gene Null polymorphism of Head and Neck Cancer Patients in Eastern India.

Asian Pacific journal of cancer prevention : APJCP - 1 Aug 2022

Surit Richa, Kumar Santosh, Sinha Dinesh Kumar, Shekhar Ravi

Abstract excerpt

OBJECTIVE: Homozygous deletion i.e., null polymorphism of the Glutathione S transferases genes hinders detoxification reactions by altering the sensitization of glutathione s transferases enzymes. Hence, we analysed the association between the GSTM1 and GSTT1 gene polymorphisms and head and neck cancer (HNC). METHODS: The study consists of 238 healthy controls and 160 diagnosed cases of HNC, who attended the...

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Case-Control Studies
Genomics
Glutathione
Glutathione Transferase
Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Deletion

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PMID: 36037119
DOI: 10.31557/APJCP.2022.23.8.2655
PMCID: PMC9741883

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