Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glutathione-S-transferase polymorphisms and risk of squamous-cell carcinoma of the head and neck.

International journal of cancer - 21 Jun 1999

Cheng L, Sturgis E M, Eicher S A, Char D, Spitz M R, Wei Q

Abstract excerpt

Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and GSTM1. In this study, we evaluated the association between GSTM1 and GSTT1 null genotypes and risk of SCCHN in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Glutathione Transferase

Share to Head and Neck Neoplasms

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 10371337
DOI: 10.1002/(sici)1097-0215(19990621)84:3<220::aid-ijc4>3.0.co;2-s

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glutathione-S-transferase polymorphisms and risk of squamous-cell carcinoma of the head and neck.PMID 10371337Read ↗

The role of GSTM1 and GSTT1 polymorphisms in head and neck cancer risk.Semantic proximity Read ↗

GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review.Semantic proximity Read ↗

Association between GSTM1 and GSTT1 allelic variants and head and neck squamous cell cancinoma.Semantic proximity Read ↗

GSTT1 and GSTM1 polymorphism in cigarette smokers with head and neck squamous cell carcinoma.Semantic proximity Read ↗

Glutathione S-transferase T1 null polymorphism and the risk for head and neck cancer.Semantic proximity Read ↗

Association of genetic polymorphisms in glutathione S-transferases and susceptibility to head and neck cancer.Semantic proximity Read ↗

Polymorphisms of GSTT1 and related genes in head and neck cancer risk.Semantic proximity Read ↗

Genetic deletions of GSTM1 and GSTT1 in head and neck cancer: review of the literature from 2000 to 2012.Semantic proximity Read ↗

Meta-analysis of glutathione S-transferase M1 genotype and risk toward head and neck cancer.Semantic proximity Read ↗

Association between GSTM1 polymorphism and nasopharyngeal cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Larynx cancer risk in relation to glutathione S-transferase M1 and T1 genotypes and tobacco smoking.Semantic proximity Read ↗

Genetic polymorphism at GSTM1 and GSTT1 gene loci and susceptibility to oral cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.