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Article

The opioid peptides enkephalin and beta-endorphin in alcohol dependence.

Biological psychiatry - 1 Dec 2008

Racz Ildiko, Schürmann Britta, Karpushova Anna, Reuter Martin, Cichon Sven, Montag Christian, Fürst Robert, Schütz Christian, Franke Petra E, Strohmaier Jana, Wienker Thomas F, Terenius Lars, Osby Urban, Gunnar Agneta, Maier Wolfgang, Bilkei-Gorzó Andras, Nöthen Markus, Zimmer Andreas

Abstract excerpt

BACKGROUND: Experimental evidence indicates that the endogenous opioid system influences stress responses as well as reinforces effects of addictive drugs. Because stress is an important factor contributing to drug dependence and relapse, we have now studied ethanol preference in enkephalin- and beta-endorphin-deficient mice under baseline conditions and after stress exposure. METHODS: In the present study we...

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Identifiers

PMID: 18589403
DOI: 10.1016/j.biopsych.2008.05.008
PMCID: PMC2646839

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POMC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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