Article
Integration of metabolic modeling and phenotypic data in evaluation and improvement of ethanol production using respiration-deficient mutants of Saccharomyces cerevisiae.
Applied and environmental microbiology - 1 Sept 2008
Dikicioglu Duygu, Pir Pinar, Onsan Z Ilsen, Ulgen Kutlu O, Kirdar Betul, Oliver Stephen G
Abstract excerpt
Flux balance analysis and phenotypic data were used to provide clues to the relationships between the activities of gene products and the phenotypes resulting from the deletion of genes involved in respiratory function in Saccharomyces cerevisiae. The effect of partial or complete respiratory deficiency on the ethanol production and growth characteristics of hap4Delta/hap4Delta, mig1Delta/mig1Delta,...
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