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Article

Metabolic engineering of glycerol production in Saccharomyces cerevisiae.

Applied and environmental microbiology - 1 Jun 2002

Overkamp Karin M, Bakker Barbara M, Kötter Peter, Luttik Marijke A H, Van Dijken Johannes P, Pronk Jack T

Abstract excerpt

Inactivation of TPI1, the Saccharomyces cerevisiae structural gene encoding triose phosphate isomerase, completely eliminates growth on glucose as the sole carbon source. In tpi1-null mutants, intracellular accumulation of dihydroxyacetone phosphate might be prevented if the cytosolic NADH generated in glycolysis by glyceraldehyde-3-phosphate dehydrogenase were quantitatively used to reduce dihydroxyacetone...

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Source

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Identifiers

PMID: 12039737
DOI: 10.1128/AEM.68.6.2814-2821.2002
PMCID: PMC123913

Genes

NDE1
TPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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