Article
Characterization of Ca2+-binding protein 5 knockout mouse retina.
Investigative ophthalmology & visual science - 1 Nov 2008
Rieke Fred, Lee Amy, Haeseleer Françoise
Abstract excerpt
PURPOSE: The goal of this study was to investigate, with the use of CaBP5 knockout mice, whether Ca(2+)-binding protein 5 (CaBP5) is required for vision. The authors also tested whether CaBP5 can modulate expressed Ca(v)1.2 voltage-activated calcium channels. METHODS: CaBP5 knockout (Cabp5(-/-)) mice were generated. The retinal morphology and visual function of 6-week-old Cabp5(-/-) mice were analyzed by confocal...
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