Article
EML1 is essential for retinal photoreceptor migration and survival.
Scientific reports - 21 Feb 2022
Poria Deepak, Sun Chi, Santeford Andrea, Kielar Michel, Apte Rajendra S, Kisselev Oleg G, Chen Shimming, Kefalov Vladimir J
Abstract excerpt
Calcium regulates the response sensitivity, kinetics and adaptation in photoreceptors. In striped bass cones, this calcium feedback includes direct modulation of the transduction cyclic nucleotide-gated (CNG) channels by the calcium-binding protein CNG-modulin. However, the possible role of EML1, the mammalian homolog of CNG-modulin, in modulating phototransduction in mammalian photoreceptors has not been...
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