Article
Using mutant mice to study the role of voltage-gated calcium channels in the retina.
Advances in experimental medicine and biology - 1 Jan 2002
Ball Sherry L, Gregg Ronald G
Abstract excerpt
Neuronal voltage-gated calcium channels (VGCCs) are critical to numerous cellular functions including synaptogenesis and neurotransmitter release. Mutations in individual subunits of VGCCs are known to result in a wide array of neurological disorders including episodic ataxia, epilepsy, and migraines. The characterization of these disorders has focused on channel function within the brain. However, a defect in...
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