Article
Algorithm for backrub motions in protein design.
Bioinformatics (Oxford, England) - 1 Jul 2008
Georgiev Ivelin, Keedy Daniel, Richardson Jane S, Richardson David C, Donald Bruce R
Abstract excerpt
MOTIVATION: The Backrub is a small but kinematically efficient side-chain-coupled local backbone motion frequently observed in atomic-resolution crystal structures of proteins. A backrub shifts the C(alpha)-C(beta) orientation of a given side-chain by rigid-body dipeptide rotation plus smaller individual rotations of the two peptides, with virtually no change in the rest of the protein. Backrubs can therefore...
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