Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

5-HT(1B) receptor knockout mice show no adaptive changes in 5-HT(1A) receptor function as measured telemetrically on body temperature and heart rate responses.

Brain research bulletin - 1 Jan 2002

Bouwknecht J Adriaan, Hijzen Theo H, van der Gugten Jan, Maes Robert A A, Hen René, Olivier Berend

Abstract excerpt

Two presynaptic receptors play an important role in the regulation of serotonergic neurotransmission, i.e., the 5-HT(1A) and 5-HT(1B) receptor. The present study focuses on putative adaptive changes in the 5-HT(1A) receptor system in mice that lack 5-HT(1B) receptors (5-HT(1B) KO). 5-HT(1A) receptor sensitivity was assessed in vivo in two models of presynaptic 5-HT(1A) receptor activity: agonist-induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Temperature
Share to Heart Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor, Serotonin, 5-HT1B

Share to Receptors, Serotonin

Share to Serotonin

Share to Serotonin Antagonists

Share to Serotonin Receptor Agonists

Share to Synaptic Transmission

Source

Identifiers

PMID: 11827741
DOI: 10.1016/s0361-9230(01)00640-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

5-HT(1B) receptor knockout mice show no adaptive changes in 5-HT(1A) receptor function as measured telemetrically on body temperature and heart rate responses.PMID 11827741Read ↗

Corticosterone responses in 5-HT1B receptor knockout mice to stress or 5-HT1A receptor activation are normal.Semantic proximity Read ↗

Interaction between 5-HT(1A) and 5-HT(1B) receptors: effects of 8-OH-DPAT-induced hypothermia in 5-HT(1B) receptor knockout mice.Semantic proximity Read ↗

5-HT1A receptor and 5-HT1B receptor knockout mice in stress and anxiety paradigms.Semantic proximity Read ↗

Characterization of serotonin neurotransmission in knockout mice: implications for major depression.Semantic proximity Read ↗

Male and female 5-HT(1B) receptor knockout mice have higher body weights than wildtypes.Semantic proximity Read ↗

The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice.Semantic proximity Read ↗

Startle responses, heart rate, and temperature in 5-HT1B receptor knockout mice.Semantic proximity Read ↗

Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice.Semantic proximity Read ↗

The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in miceSemantic proximity Read ↗

Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal development.Semantic proximity Read ↗

Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats.Semantic proximity Read ↗

The 5-HT(1A) receptor knockout mouse and anxiety.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.