Article
[Comparison of antiviral responses to adefovir dipivoxil therapy of genotype B and genotype C HBV infected patients].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jun 2008
Zeng Ai-zhong, Deng Hui, Peng Feng-ying, Xin Xiao-juan, Yang Chun, Li Qing-ling, Guo Jin-jun, Zhang Zhen-zhen, Hao Mei-jun, Yuan Zhe, Huang Wen-xiang, Huang Ai-long
Abstract excerpt
OBJECTIVE: To investigate the role of HBV genotypes on their response to adefovir dipivoxil (ADV) antiviral therapy. METHODS: HBV genotypes from 177 HBeAg-positive chronic hepatitis B (CHB) patients were identified and the patients were treated with ADV 10 mg per day for 48 weeks. The clinical data in terms of serum HBV DNA seroclearance, mean HBV DNA reduction (log value), HBeAg loss, anti-HBe seroconversion and...
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