Article
[Correlation of HBV genotypes to the therapeutic effect of PEG-interferon and the pathological changes of the liver of chronic hepatitis B patients].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2008
Shen Jian-kun, Hou Jin-lin, Pang Xin-nan, Yang Hong, Xu Zheng-ju
Abstract excerpt
OBJECTIVE: To study the correlation of HBV genotypes to the response to PEG-interferon alpha (PEG-IFN) in chronic hepatitis B (CHB) patients. METHODS: Real-time fluorescent PCR was used for HBV genotyping in 48 CHB patients, and the therapeutic effects of PEG-IFN and hepatic pathological changes were observed. RESULTS: No obvious differences were noted in ALT and HBV DNA levels or negative rate for HBeAg between...
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