Article
Hepatitis B virus genotype-associated variability in antiviral response to adefovir dipivoxil therapy in Chinese Han population.
The Tohoku journal of experimental medicine - 1 Nov 2008
Zeng Ai-Zhong, Deng Hui, Yang Chung, Xin Xiao-Juan, Li Qing-Ling, Guo Jin-Jun, Lu Ping, Huang Ai-Long
Abstract excerpt
It is well known that different genotypes of hepatitis B virus (HBV) have a different sensitivity to interferon-alpha or lamivudine (nucleoside analogue) antiviral therapy. However, for adefovir dipivoxil (ADV, a nucleotide analogue), the antiviral response of the different genotypes remains to be clarified. In order to evaluate the response of HBV genotypes to ADV therapy and to identify factors that might...
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