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Article

Retroviral pseudotransduction for targeted cell manipulation.

Molecular cell - 22 Oct 2004

Galla Melanie, Will Elke, Kraunus Janine, Chen Lei, Baum Christopher

Abstract excerpt

The present study addressed whether retroviral vectors could be modified to achieve receptor-mediated, dose-controlled, and transient delivery of proteins or nucleic acids into targeted cells. As a paradigm, we generated mouse leukemia virus-based vectors encoding the site-specific recombinase Cre. The vectors were disabled in primer binding site function, blocking reverse transcription of the virion mRNA. While...

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Identifiers

PMID: 15494317
DOI: 10.1016/j.molcel.2004.09.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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