Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated genomic and transcriptional analysis of the in vitro evolution of telomerase-immortalized urothelial cells (TERT-NHUC).

Genes, chromosomes & cancer - 1 Aug 2009

Chapman Emma J, Williams Sarah V, Platt Fiona M, Hurst Carolyn D, Chambers Philip, Roberts Paul, Knowles Margaret A

Abstract excerpt

Much progress has been made in identifying the molecular genetic alterations that occur in bladder cancer. However, in many cases the genes targeted by these alterations are not known. Telomerase immortalized human urothelial cells (TERT-NHUC) are a useful resource for in vitro studies of genes involved in urothelial transformation. When cultured under standard conditions they remain genetically stable but when...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Ploidies

Share to Telomerase

Share to Urinary Bladder Neoplasms

Share to Urothelium

Source

Identifiers

PMID: 19405089
DOI: 10.1002/gcc.20672

Genes

TERT
BOK
FRAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated genomic and transcriptional analysis of the in vitro evolution of telomerase-immortalized urothelial cells (TERT-NHUC).PMID 19405089Read ↗

Genes Involved in Differentiation, Stem Cell Renewal, and Tumorigenesis Are Modulated in Telomerase-Immortalized Human Urothelial CellsSemantic proximity Read ↗

The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial TumorsSemantic proximity Read ↗

Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer.Semantic proximity Read ↗

Re: A Genetically Defined Disease Model Reveals that Urothelial Cells Can Initiate Divergent Bladder Cancer Phenotypes.Semantic proximity Read ↗

Re: A Genetically Defined Disease Model Reveals That Urothelial Cells Can Initiate Divergent Bladder Cancer Phenotypes.Semantic proximity Read ↗

The evolving genomic landscape of urothelial carcinomaSemantic proximity Read ↗

Target genes of recurrent chromosomal amplification and deletion in urothelial carcinoma.Semantic proximity Read ↗

TERT promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance.Semantic proximity Read ↗

Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.Semantic proximity Read ↗

<i>TERT</i> promoter mutations and telomerase reactivation in urothelial cancerSemantic proximity Read ↗

Emerging targets in upper tract urothelial carcinomas: the TERT gene.Semantic proximity Read ↗

Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.