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Article

Modulation of alphaCaMKII signaling by rapid ERalpha action.

Brain research - 30 Jul 2008

O'Neill Erin E, Blewett Alexis R, Loria Paula M, Greene Geoffrey L

Abstract excerpt

The estrogen receptor (ER) subtypes, ERalpha and ERbeta, modulate numerous signaling cascades in the brain to result in a variety of cell fates including neuronal differentiation. We report here that 17beta-estradiol (E2) rapidly stimulates the autophosphorylation of alpha-Ca(2+)/calmodulin-dependent kinase II (alphaCaMKII) in immortalized NLT GnRH neurons, primary hippocampal neurons, and Cos7 cells...

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Source

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Identifiers

PMID: 18572149
DOI: 10.1016/j.brainres.2008.05.036
PMCID: PMC2597455

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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