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Article

Comparison of two-phase analyses for case-control genetic association studies.

Statistics in medicine - 30 Oct 2008

Zheng Gang, Meyer Mark, Li Wentian, Yang Yaning

Abstract excerpt

To test for genetic association between a marker and a complex disease using a case-control design, Cochran-Armitage trend tests (CATTs) and Pearson's chi-square test are often employed. Both tests are genotype-based. Song and Elston (Statist. Med. 2006; 25:105-126) introduced the Hardy-Weinberg disequilibrium trend test and combined it with CATT to test for association. Compared to using a single statistic to...

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PMID: 18570272
DOI: 10.1002/sim.3336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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