Article
Lack of association of delta-aminolevulinate dehydratase polymorphisms with blood lead levels and hemoglobin in Romanian women from a lead-contaminated region.
Journal of toxicology and environmental health. Part A - 1 Jan 2008
Rabstein Sylvia, Unfried Klaus, Ranft Ulrich, Illig Thomas, Kolz Melanie, Mambetova Chinara, Vlad Mariana, Roman Cecilia, Weiss Tobias, Becker Doreen, Brüning Thomas, Pesch Beate
Abstract excerpt
As part of a project on environmental pollution, this study aimed to evaluate associations between blood lead (BPb) levels, hemoglobin (Hb) content, and single-nucleotide polymorphisms (SNPs) of delta-aminolevulinic acid dehydratase (ALAD) gene in 129 unrelated women from Romania. Five SNPs (rs1805313, rs2228083, rs1805312, rs1800435, rs1139488) were analyzed with respect to haplotype structure and impact on BPb...
