Article
The RR genotype of codon 72 of p53 gene reduces the development of intestinal metaplasia.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Mar 2009
Szoke D, Molnár B, Solymosi N, Sipos F, Galamb O, Gyorffy A, Tulassay Z
Abstract excerpt
BACKGROUND AND AIMS: Mutations of p53 gene can contribute to the development of gastric cancer. Our aims were to evaluate the premalignant gastric intestinal metaplasia-related p53 alterations, using and comparing capillary sequencing and p53 resequencing chip in gastric biopsy and peripheral blood samples. Furthermore we examined the effect of p53 polymorphism on the protein expression level. PATIENTS AND...
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