Article
The discrepancy between genetic polymorphism of p53 codon 72 and the expression of p53 protein in Helicobacter pylori-associated gastric cancer in Korea.
Digestive diseases and sciences - 1 Jan 2010
Kim Nayoung, Cho Sung-Il, Lee Hye Seung, Park Ji Hyun, Kim Jee Hyun, Kim Joo Sung, Jung Hyun Chae, Song In Sung
Abstract excerpt
The p53 gene has been referred to as 'the guardian of the genome' because it controls apoptosis and cell cycle arrest. The purpose of this study was to evaluate the association of p53 codon 72 genetic polymorphism and the p53 immunohistochemistry with Helicobacter pylori-associated gastroduodenal diseases, including gastric cancer. This study included 1,852 subjects: controls and patients with gastric cancer,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
