Article
Helicobacter pylori infection and a P53 codon 72 single nucleotide polymorphism: a reason for an unexplained Asian enigma.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Pandey Renu, Misra Vatsala, Misra Sri Prakash, Dwivedi Manisha, Misra Alok
Abstract excerpt
AIM: P53, the most commonly mutated tumor suppressor gene in all types of human cancer, is involved in cell cycle arrest and control of apoptosis. Although p53 contains several polymorphic sites, the codon 72 polymorphism is by far more common. There are divergent reports but many studies suggest p53 pro/pro SNP may be associated with susceptibility to developing various cancers in different regions of the world....
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