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Article

A genome-wide assessment of rare copy number variants in colorectal cancer.

Oncotarget - 22 Sept 2015

Li Zhenli, Yu Dan, Gan Meifu, Shan Qiaonan, Yin Xiaoyang, Tang Shunli, Zhang Shuai, Shi Yongyong, Zhu Yimin, Lai Maode, Zhang Dandan

Abstract excerpt

Colorectal cancer (CRC) is a complex disease with an estimated heritability of approximately 35%. However, known CRC-related common single nucleotide polymorphisms (SNPs) can only explain ~0.65% of the heritability. This "missing heritability" may be explained partially by rare copy number variants (CNVs). In this study, we performed a genome-wide scan using Illumina Human-Omni Express BeadChip, 694 sporadic CRC...

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Identifiers

PMID: 26315111
DOI: 10.18632/oncotarget.4621
PMCID: PMC4694911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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