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Article

Genome-wide association study identified copy number variants associated with sporadic colorectal cancer risk.

Journal of medical genetics - 1 Mar 2018

Thean Lai Fun, Low Yee Syuen, Lo Michelle, Teo Yik-Ying, Koh Woon-Puay, Yuan Jian-Min, Chew Min Hoe, Tang Choong Leong, Cheah Peh Yean

Abstract excerpt

BACKGROUND: Multiple single nucleotide polymorphisms (SNPs) have been associated with colorectal cancer (CRC) risk. The role of structural or copy number variants (CNV) in CRC, however, remained unclear. We investigated the role of CNVs in patients with sporadic CRC. METHODS: A genome-wide association study (GWAS) was performed on 1000 Singapore Chinese patients aged 50 years or more with no family history of CRC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29079706
DOI: 10.1136/jmedgenet-2017-104913

Genes

CHD8
ARHGDIB
RERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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