Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the bHLH Factor Math6 as a Novel Component of the Embryonic Pancreas Transcriptional Network

17 Jun 2008

Abstract excerpt

BACKGROUND: Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. In the pancreas, the atonal-related bHLH gene Neurogenin3 (Neurog3) controls endocrine cell fate specification in uncommitted progenitor cells. Therefore, it is likely that Neurog3-regulated factors will have important functions during pancreatic endocrine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Developmental Biology and Gene Regulation
Share to Pancreatic function and diabetes
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18560595
DOI: 10.1371/journal.pone.0002430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the bHLH Factor Math6 as a Novel Component of the Embryonic Pancreas Transcriptional NetworkPMID 18560595Read ↗

Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene <i>ngn3</i>Semantic proximity Read ↗

Defining Pancreatic Endocrine Precursors and Their DescendantsSemantic proximity Read ↗

NEUROD1: transcriptional and epigenetic regulator of human and mouse neuronal and endocrine cell lineage programsSemantic proximity Read ↗

Basic helix‐loop‐helix transcription factors and enteroendocrine cell differentiationSemantic proximity Read ↗

Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.Semantic proximity Read ↗

Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitorsSemantic proximity Read ↗

Gata6 is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult miceSemantic proximity Read ↗

Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.Semantic proximity Read ↗

The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiationSemantic proximity Read ↗

Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube.Semantic proximity Read ↗

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.Semantic proximity Read ↗

Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.