Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of megalin genetic polymorphisms with prostate cancer risk and prognosis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2008

Holt Sarah K, Karyadi Danielle M, Kwon Erika M, Stanford Janet L, Nelson Peter S, Ostrander Elaine A

Abstract excerpt

PURPOSE: Megalin, an endocytic receptor expressed by prostate epithelial cells, can internalize biologically active androgens bound to sex hormone binding globulin. Genetic variation within megalin could potentially influence levels of steroid hormone uptake. EXPERIMENTAL DESIGN: Forty haplotype-tagging single-nucleotide polymorphisms (htSNP) were analyzed in a population-based, case-control study of 553...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Low Density Lipoprotein Receptor-Related Protein-2

Share to Prognosis

Share to Prostatic Neoplasms

Share to Recurrence

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 18559602
DOI: 10.1158/1078-0432.CCR-07-4566
PMCID: PMC2675883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of megalin genetic polymorphisms with prostate cancer risk and prognosis.PMID 18559602Read ↗

Population-based study of the association of variants in mismatch repair genes with prostate cancer risk and outcomes.Semantic proximity Read ↗

Prostate cancer predisposition loci and risk of metastatic disease and prostate cancer recurrence.Semantic proximity Read ↗

A Multigene-Panel Study Identifies Single Nucleotide Polymorphisms Associated with Prostate Cancer Risk.Semantic proximity Read ↗

Genetic variants in the Hippo pathway predict biochemical recurrence after radical prostatectomy for localized prostate cancer.Semantic proximity Read ↗

Vitamin D pathway gene variants and prostate cancer prognosis.Semantic proximity Read ↗

Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.Semantic proximity Read ↗

Association of hepsin gene variants with prostate cancer risk and prognosis.Semantic proximity Read ↗

Associations between RNA splicing regulatory variants of stemness-related genes and racial disparities in susceptibility to prostate cancer.Semantic proximity Read ↗

SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death.Semantic proximity Read ↗

Prognostic Relevance of Methylenetetrahydrofolate Reductase Polymorphisms for Prostate Cancer.Semantic proximity Read ↗

Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk.Semantic proximity Read ↗

Genetic variants in RhoA and ROCK1 genes are associated with the development, progression and prognosis of prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.