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Article

Genetic variants in the Hippo pathway predict biochemical recurrence after radical prostatectomy for localized prostate cancer.

Scientific reports - 24 Feb 2015

Huang Chao-Yuan, Huang Shu-Pin, Lin Victor C, Yu Chia-Cheng, Chang Ta-Yuan, Juang Shin-Hun, Bao Bo-Ying

Abstract excerpt

While localized prostate cancer is potentially curative, many patients still show biochemical recurrence (BCR) after curative treatments such as radical prostatectomy (RP). The Hippo pathway has recently been shown to be an evolutionarily conserved regulator of tissue growth, and its perturbation can trigger tumorigenesis. We hypothesize that genetic variants of the Hippo pathway may influence clinical outcomes...

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Identifiers

PMID: 25707771
DOI: 10.1038/srep08556
PMCID: PMC4338420

Genes

BCR
STK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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