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Article

Prostate cancer predisposition loci and risk of metastatic disease and prostate cancer recurrence.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2011

Ahn Jiyoung, Kibel Adam S, Park Jong Y, Rebbeck Timothy R, Rennert Hanna, Stanford Janet L, Ostrander Elaine A, Chanock Stephen, Wang Ming-Hsi, Mittal Rama D, Isaacs William B, Platz Elizabeth A, Hayes Richard B

Abstract excerpt

PURPOSE: Genome-wide association studies (GWAS) have identified multiple novel prostate cancer predisposition loci. Whether these common genetic variants are associated with incident metastatic prostate cancer or with recurrence after surgical treatment for clinically localized prostate cancer is uncertain. EXPERIMENTAL DESIGN: Twelve single nucleotide polymorphisms (SNPs) were selected for study in relation to...

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PMID: 21343373
DOI: 10.1158/1078-0432.CCR-10-0881
PMCID: PMC3059497

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