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Article

Genetic variants in RhoA and ROCK1 genes are associated with the development, progression and prognosis of prostate cancer.

Oncotarget - 21 Mar 2017

Liu Kang, Li Xiao, Wang Jie, Wang Yichun, Dong Huiyu, Li Jie

Abstract excerpt

The contribution of genetic variants in RhoA and ROCK1 genes towards prostate cancer risk has not been reported before. We genotyped six potentially functional genetic variants in a case-control study of 1699 subjects. Overall, we found rs2410 mutant allele and rs2269736 wild allele were risk factors for prostate cancer. Individuals carrying more than two risk alleles were exposed to hazard of prostate cancer. In...

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Identifiers

PMID: 28184030
DOI: 10.18632/oncotarget.15197
PMCID: PMC5386685

Genes

ROCK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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