Article
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2008
Duell Eric J, Bracci Paige M, Moore Jason H, Burk Robert D, Kelsey Karl T, Holly Elizabeth A
Abstract excerpt
Data mining and data reduction methods to detect interactions in epidemiologic data are being developed and tested. In these analyses, multifactor dimensionality reduction, focused interaction testing framework, and traditional logistic regression models were used to identify potential interactions with up to three factors. These techniques were used in a population-based case-control study of pancreatic cancer...
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