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Association and Intragenic Single-Nucleotide Polymorphism Interactions of the XRCC1 Polymorphisms for Pancreatic Cancer Susceptibility.

Pancreas - 1 Apr 2016

Hou Bao-Hua, Jian Zhi-Xiang, Cui Peng, Li Shao-Jie, Tian Rui-Qing, Ou Jin-Rui

Abstract excerpt

OBJECTIVES: X-ray repair cross-complementing group 1 (XRCC1) gene is an important candidate gene for influencing human cancer risks. This study examined the main and interactive effect of 9 single-nucleotide polymorphisms (SNPs) (Arg194Trp, Arg280His, Arg399Gln, c.1254C>T, c.1517G>C, c.1471G>A, C310T, 539del542, and T1915C) of XRCC1 in contribution to pancreatic cancer (PC). METHODS: A total of 298 PC patients...

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Identifiers

PMID: 26418909
DOI: 10.1097/MPA.0000000000000482

Genes

XRCC1

Variants

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