Article
Kernel-based association test.
Genetics - 1 Jun 2008
Yang Hsin-Chou, Hsieh Hsin-Yi, Fann Cathy S J
Abstract excerpt
Association mapping (i.e., linkage disequilibrium mapping) is a powerful tool for positional cloning of disease genes. We propose a kernel-based association test (KBAT), which is a composite function of "P-values of single-locus association tests" and "kernel weights related to intermarker distances and/or linkage disequilibria." The KBAT is a general form of some current test statistics. This method can be...
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