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Article

Alternative splicing and the progesterone receptor in breast cancer

30 May 2008

Abstract excerpt

Progesterone receptor status is a marker for hormone responsiveness and disease prognosis in breast cancer. Progesterone receptor negative tumours have generally been shown to have a poorer prognosis than progesterone receptor positive tumours. The observed loss of progesterone receptor could be through a range of mechanisms, including the generation of alternatively spliced progesterone receptor variants that...

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Identifiers

PMID: 18557990
DOI: 10.1186/bcr2097

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